“通過(guò)高壓臥式珠(球)磨機(jī)生產(chǎn)的藥物納米晶體。高壓臥式珠(球)磨機(jī)已經(jīng)應(yīng)用在生產(chǎn)乳液和懸浮液的各個(gè)領(lǐng)域中多年,并且目前用于食品工業(yè),例如牛奶的均質(zhì)化。該技術(shù)的一個(gè)明顯優(yōu)勢(shì)是易于擴(kuò)展,甚至可以擴(kuò)展到非常大的容量。在制藥工業(yè)中,通過(guò)該技術(shù)生產(chǎn)腸胃外乳液?!?/p>
圖:采用再循環(huán)方法的珠(球)磨機(jī)Dispermat SL示意圖
“Drug Nanocrystals produced by High- Pressure Homogenization. High-pressure homogenization has been applied for many years in various areas for the production of emulsions and suspensions and is currently used in food industry like homogenization of milk. A distinct advantage of this technology is its ease for scaling up, even to very large volumes. In the pharmaceutical industry parenteral emulsions are produced by this technology.”